Resveratrol improves cognitive performance in menopausal women: Study

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The peer-reviewed research, published in Clinical Nutrition​, noted that “Ageing and menopause contribute to endothelial dysfunction, causing impaired cerebral perfusion, which is in turn associated with accelerated cognitive decline.”

Marcia da Silva Pinto, PhD, Evolva’s Technical Sales and Customer Support Manager, said cognitive decline is indeed a common health challenge in postmenopausal women: “The decrease in estrogen levels, commonly experienced during menopause, is critical in leading to health issues not only related to cognitive health, but also circulatory, bone health and quality of life that can be seriously impacted by these issues.”

Previous studies showed that supplementation with low-dose resveratrol, a phytoestrogen that has been reported to enhance endothelial function, improved cerebrovascular and cognitive functions in postmenopausal women. The study aimed to confirm the previous findings in a larger, longer-term study.

The new study, conducted at the University of Newcastle’s Clinical Nutrition Research Centre, Australia, is the third installation of anticipated publications from the extensive two-year RESHAW clinical trial of Veri-te resveratrol.

The other two peer-reviewed publications from the RESHAW study have reported the cerebrovascular and cognitive benefits, as well as bone mineral density improvements in postmenopausal women. 

Study details 

A 24-month randomized, placebo-controlled crossover trial was undertaken in 125 postmenopausal women, aged 45-85 years. The participants took 75 mg trans-resveratrol or placebo twice a day for 12 months and then crossed over to the alternative treatment for another 12 months. 

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